Covid19 Drug Dexamethasone Discovered
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_This information was souced from CNN news and brought to you By;
Medis-Health Nigeria_
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A cheap and widely available drug can help save the lives of patients seriously ill.
It cut the risk of death by a third for patients on ventilators. For those on oxygen, it cut deaths by a fifth.
up to 5,000 lives could have been saved, researchers say.
And these are the high-risk patients dexamethasone appears to help.
The drug is already used to reduce inflammation in a range of other conditions, including arthritis, asthma and skin some conditions. And it appears to help stop some of the damage that can happen when the body’s immune system goes into overdrive as it tries to fight off coronavirus.
For patients on ventilators, it cut the risk of death from 40% to 28%. For patients needing oxygen, it cut the risk of death from 25% to 20%.
Lead researcher Prof Martin Landray said the findings suggested one life could be saved for: every eight patients on a ventilator every 20-25 treated with oxygen “There is a clear, clear benefit,” he said.
“The treatment is up to 10 days of dexamethasone and it costs about £5 per patient. “So essentially it costs £35 to save a life. “This is a drug that is globally available.” When appropriate, hospital patients should now be given it without delay, Prof Landray said.
But people should not go out and buy it to take at home. Dexamethasone does not appear to help people with milder symptoms of coronavirus who do not need help with their breathing. The Recovery Trial, running since March, also looked at the malaria drug hydroxychloroquine, which has subsequently been ditched amid concerns it increases fatalities and heart problems.
The antiviral drug remdesivir, meanwhile, which appears to shorten recovery time for people with coronavirus, is already being made available on the NHS. The first drug proven to cut deaths from Covid-19 is not some new, expensive medicine but an old, cheap-as-chips steroid.
That is something to celebrate because it means patients across the world could benefit immediately. And that is why the top-line results of this trial have been rushed out – because the implications are so huge globally. Dexamethasone has been used since the early 1960s to treat a wide range of conditions, such as rheumatoid arthritis and asthma.
Half of all Covid patients who require a ventilator do not survive, so cutting that risk by a third would have a huge impact. The drug is given intravenously in intensive care and in tablet form for less seriously ill patients. So far, the only other drug proven to benefit Covid patients is remdesivir, which has been used for Ebola. That has been shown to reduce the duration of coronavirus symptoms from 15 days to 11.
But the evidence was not strong enough to show whether it reduced mortality. Unlike dexamethasone, remdesivir is a new drug with limited supplies and a price has yet to be announced.
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